Low pain perception was defined as a score of one, two or three moderate pain perception was a score of four, five or six and high pain perception was a score of seven, eight, nine or 10. People who rated their pain as zero were not included in the study. The participants also rated their perception of pain on a scale from zero to 10. The genes involved were COMT, DRD2, DRD1 and OPRK1. Participants were taking prescription opioid pain medications.
Researchers evaluated 2,721 people diagnosed with chronic pain for certain genes. “Identifying whether a person has these four genes could help doctors better understand a patient’s perception of pain.” “Our study is quite significant because it provides an objective way to understand pain and why different individuals have different pain tolerance levels,” said study author Tobore Onojjighofia, MD, MPH, with Proove Biosciences and a member of the American Academy of Neurology. Researchers may have identified key genes linked to why some people have a higher tolerance for pain than others, according to a study released today that will be presented at the American Academy of Neurology’s 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014. Home Press Room Archives Press Release EMBARGOED FOR RELEASE UNTIL 4 PM ET, ApLow Tolerance for Pain? The Reason May Be In Your Genes We’re experiencing unusually high levels of traffic. The latest research and news affecting neurology.A network of 38,000+ neurologists and neuroscience professionals.Guidelines and publications including Neurology® journal.
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